Congratulations to Alice REFEYTON, Marija Vlaski-Lafarge and the EFS research team in Bordeaux directed by Zoran Ivanovic, part of MRGM : Maladies Rares Génétiques et Métabolisme laboratory Inserm U1211. An original alternative pathway for OXPHOS fueling is discovered in this work with implications for human stem cells therapy. Great collaboration with Milos Filipovic team.
Département Sciences Biologiques et Médicales Université de Bordeaux CELLOMET
Milos Filipovic • ERC SULFAGING group
Happy to share our latest collaborative work, now published in Redox Biology. A surprising discovery that human mesenchymal stem cells can sustain mitochondrial ATP production under anoxia and aglycemia through an alternative electron transport pathway fueled by sulfide oxidation, revealing an unexpected metabolic flexibility of mammalian mitochondria. Big thank you to Marija Vlaski-Lafarge , Zoran Ivanovic for friendship first and for leting me be part of this.
https://www.sciencedirect.com/science/article/pii/S2213231726003034?via%3Dihub